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Chemical Structure : SR10221
Catalog No.: PC-49401Not For Human Use, Lab Use Only.
SR10221 is a potent, selective PPARγ inverse agonist with IC50 of 13 nM in biochemical peptide recruitment assays, represses downstream PPARγ target genes leading to growth inhibition in bladder cancer cell lines.
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SR10221 is a potent, selective PPARγ inverse agonist with IC50 of 13 nM in biochemical peptide recruitment assays, represses downstream PPARγ target genes leading to growth inhibition in bladder cancer cell lines.
| M.Wt | 561.119 | |
| Formula | C33H37ClN2O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Sean Irwin, et al. J Biol Chem. 2022 Sep 28;298(11):102539.
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