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SR 21502

Chemical Structure : SR 21502

CAS No.: 1596371-76-4

SR 21502 (SR21502)

Catalog No.: PC-25208Not For Human Use, Lab Use Only.

SR 21502 is a potent, selective D3 dopamine receptor (D3R) antagonist with Ki of 4.2 nM, >120-fold binding selectivity over D2 receptor.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

SR 21502 is a potent, selective D3 dopamine receptor (D3R) antagonist with Ki of 4.2 nM, >120-fold binding selectivity over D2 receptor.

Physicochemical Properties

M.Wt 503.57
Formula C25H32F3N7O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(4-(4-(2-(tert-butyl)-6-(trifluoromethyl)pyrimidin-4-yl)piperazin-1-yl)butyl)imidazo[1,2-a]pyridine-2-carboxamide

References

1. Galaj E, A, et al. Psychopharmacology (Berl). 2014 Feb;231(3):501-10.

2. Hachimine P, et al. Neurosci Lett. 2014 May 21;569:137-41.

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