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Chemical Structure : STAT5-IN-1
CAS No.: 285986-31-4
Catalog No.: PC-61311Not For Human Use, Lab Use Only.
STAT5-IN-1 is a selective, small molecule inhibitor of the transcription factor STAT5 with IC50 of 47±17 uM in FP assays.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $178 | In stock | |
| 50 mg | $328 | In stock | |
| 100 mg | $528 | In stock | |
| 250 mg | Get quote |
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STAT5-IN-1 is a selective, small molecule inhibitor of the transcription factor STAT5 with IC50 of 47±17 uM in FP assays.
STAT5-IN-1 shows little to no inhibition for STAT1, STAT3 and Lck (<40% inhibition at 500 uM).
STAT5-IN-1 selectively inhibits the function of the STAT5b domain and STAT5 DNA binding in vitro, and selectively inhibits activation of STAT5 in K562 cells.
| M.Wt | 293.28 | |
| Formula | C16H11N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
3-Pyridinecarboxylic acid, [(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazide (9CI) |
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1. Müller J, et al. Chembiochem. 2008 Mar 25; 9(5):723-7.
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