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STAT6-IN-9

Chemical Structure : STAT6-IN-9

CAS No.: 3092076-15-5

STAT6-IN-9

Catalog No.: PC-25690Not For Human Use, Lab Use Only.

STAT6-IN-9 is a potent, selective STAT6 inhibitor with EC50 of 4 nM, efficiently blocks the STAT6 activation process mediated by the IL-13-IL-13 receptor/IL-4 receptor pathway, potently inhibits CCL17 secretion with IC50 of 4.6 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

STAT6-IN-9 is a potent, selective STAT6 inhibitor with EC50 of 4 nM, efficiently blocks the STAT6 activation process mediated by the IL-13-IL-13 receptor/IL-4 receptor pathway, potently inhibits CCL17 secretion with IC50 of 4.6 nM.

Physicochemical Properties

M.Wt 568.68
Formula C31H36N8O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1H-Indazole-3-carboxamide, 5-[5-[(dimethylamino)carbonyl]-2-pyridinyl]-1-ethyl-N-[[4-[[(4-methyl-1-piperazinyl)carbonyl]amino]phenyl]methyl]-

References

1. Patent WO2025133961 A1.

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