Chemical Structure : SU5402
CAS No.:
215543-92-3
SU5402
(SU-5402, SU 5402)
Catalog No. : PC-42567Not For Human Use, Lab Use Only.
SU5402 is a multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGFRβ, respectively.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4256701
Biological Activity
SU5402 is a multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2 , FGFR1 , and PDGFRβ, respectively.
Physicochemical Properties
M.Wt
296.3205
Formula
C17H16N2O3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 30 mg/mL
Chemical Name/SMILES
1H-Pyrrole-3-propanoic acid, 2-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-4-methyl-
References
1. Mohammadi M, et al. Science
2. Udayakumar TS, et al. Int J Cancer.
3. Hoffman MP, et al. Development.
4. Grand EK, et al. Leukemia.
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