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Chemical Structure : SU 5402
CAS No.: 215543-92-3
Catalog No.: PC-42567Not For Human Use, Lab Use Only.
A selective FGFR1 inhibitor with IC50 of 10-20 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $80 | In stock | |
| 50 mg | $280 | In stock | |
| 100 mg | $496 | In stock |
Bulk size, bulk discount!
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A selective FGFR1 inhibitor with IC50 of 10-20 uM; does not inhibit tyrosine phosphorylation of PDGFR and EGFR (IC50>200 uM), weakly inhibits insulin receptor; specifically inhibits the growth of the t(4;14)-positive MM lines, KMS-11 and OPM-2, reduces cell viability and increases apoptosis.
| M.Wt | 296.3205 | |
| Formula | C17H16N2O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 30 mg/mL |
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| Chemical Name/SMILES |
1H-Pyrrole-3-propanoic acid, 2-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-4-methyl- |
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2. Udayakumar TS, et al. Int J Cancer. 2001 Jan 15;91(2):187-92.
3. Hoffman MP, et al. Development. 2002 Dec;129(24):5767-78.
4. Grand EK, et al. Leukemia. 2004 May;18(5):962-6.
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