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Chemical Structure : SYP-5
CAS No.: 1384268-04-5
Catalog No.: PC-42229Not For Human Use, Lab Use Only.
A novel potent HIF-1 inhibitor that inhibits hypoxia-induced upregulation of HIF-1, suppresses tumor cells invasion and angiogenesis.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $264 | In stock | |
| 10 mg | $400 | In stock | |
| 50 mg | $1200 | In stock | |
| 100 mg | $1680 | In stock |
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A novel potent HIF-1 inhibitor that inhibits hypoxia-induced upregulation of HIF-1, suppresses tumor cells invasion and angiogenesis; down-regulates VEGF and MMP-2, suppresses angiogenesis induced by hypoxia and VEGF in vitro; inhibits tumor cell migration and invasion by suppressing PI3K/AKT- and MAPK/ERK-dependent HIF-1 pathway.
| M.Wt | 312.3828 | |
| Formula | C18H16O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2-Propen-1-one, 1-(5-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-3-(2-thienyl)-, (2E)- |
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1. Wang LH, et al. Eur J Pharmacol. 2016 Nov 15;791:560-568.
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