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Chemical Structure : Sabatolimab
CAS No.:
Catalog No.: PC-Ab1017Not For Human Use, Lab Use Only.
Binds and blocks the interaction TIM3/PtdSer (Kd=0.16 nM, PtdSer Blocking IC50=6.4 nM) , restore effector T cell activity to promote antitumor immunity by altering myeloid cells in tumor microenvironment. TIM-3 may synergize with PD-1 blockade by enhancing or altering the innate immune response and may form part of a resistance mechanism to PD-1 blockade..
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 1 mg | $358 | In stock | |
| 5 mg | $758 | In stock | |
| 10 mg | $1280 | In stock | |
| 100 mg | Get quote |
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Binds and blocks the interaction TIM3/PtdSer (Kd=0.16 nM, PtdSer Blocking IC50=6.4 nM) , restore effector T cell activity to promote antitumor immunity by altering myeloid cells in tumor microenvironment. TIM-3 may synergize with PD-1 blockade by enhancing or altering the innate immune response and may form part of a resistance mechanism to PD-1 blockade.
| M.Wt | ||
| Formula | Human IgG4 (S228P)-Kappa | |
| Appearance | Solid | |
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| Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
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