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Salvinorin A

Chemical Structure : Salvinorin A

CAS No.: 83729-01-5

Salvinorin A (Salvinorin)

Catalog No.: PC-26942Not For Human Use, Lab Use Only.

Salvinorin A is a potent, selective and high efficacy kappa-opioid receptor (KOR) agonist with Ki value of 4.3 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Salvinorin A is a potent, selective and high efficacy kappa-opioid receptor (KOR) agonist with Ki value of 4.3 nM.
Salvinorin A is a neoclerodane diterpene and active component of S. divinorum.
Salvinorin A has short lasting effects in vivo and limited oral bioavailability, probably due to acetate metabolism.
Salvinorin A profoundly alters consciousness and perception in vivo.

Physicochemical Properties

M.Wt 432.47
Formula C23H28O8
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-acetoxy-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxododecahydro-2H-benzo[f]isochromene-7-carboxylate

References

1. Butelman ER, et al. Front Pharmacol. 2015 Sep 8;6:190.

2. John TF, et al. Eur J Pharmacol. 2006 Sep 18;545(2-3):129-33.

3. Béguin C, et al. J Pharmacol Exp Ther. 2008 Jan;324(1):188-95.

4. Munro TA, et al. J Med Chem. 2005 Jan 27;48(2):345-8.

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