Chemical Structure : Sauchinone
CAS No.: 177931-17-8
Catalog No.: PC-24477Not For Human Use, Lab Use Only.
Sauchinone is a diastereomeric lignan isolated from Saururus chinensis with anti-inflammatory and antioxidant activity, inhibits LPS-inducible iNOS, TNF-α and COX-2 expression through suppression of I-κBα phosphorylation and p65 nuclear translocation, also is a novel TGR5 agonist.
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Sauchinone is a diastereomeric lignan isolated from Saururus chinensis with anti-inflammatory and antioxidant activity, inhibits LPS-inducible iNOS, TNF-α and COX-2 expression through suppression of I-κBα phosphorylation and p65 nuclear translocation, also is a novel TGR5 agonist.
M.Wt | 356.37 | |
Formula | C20H20O6 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(5aR,5a1R,7R,8S,8aR,14aS)-7,8-Dimethyl-5a,5a1,6,7,8,8a-hexahydro-5H-benzo[kl]bis([1,3]dioxolo)[4,5-b:4',5'-g]xanthen-5-one |
1. Lee AK, et al. Br J Pharmacol. 2003 May;139(1):11-20.
2. Wang HY, et al. J Adv Res. 2025 Apr 22:S2090-1232(25)00278-4.
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