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Chemical Structure : Senile plaques (SPs) probe BSB
CAS No.: 291766-06-8
Catalog No.: PC-38734Not For Human Use, Lab Use Only.
Senile plaques (SPs) probe BSB is a chemical probe that can detect accumulation of Aβ in senile plaques (SPs) in vivo, exhibits high binding affinity for Aβ aggregates in vitro (Ki=0.4 uM).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $198 | In stock | |
| 25 mg | $348 | In stock | |
| 50 mg | $558 | In stock | |
| 100 mg | Get quote |
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Senile plaques (SPs) probe BSB is a chemical probe that can detect accumulation of Aβ in senile plaques (SPs) in vivo, exhibits high binding affinity for Aβ aggregates in vitro (Ki=0.4 uM).
BSB specifically labels SPs in postmortem AD brain sections with excellent fluorescent properties (λab = 340 nm; λem = 520 nm) and lipophilicity.
BSB effectively labels Aβ aggregates in vivo.
BSB shows potential as an antemortem diagnostic for Alzheimer's disease (AD).
| M.Wt | 481.298 | |
| Formula | C24H17BrO6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
1-Bromo-2,5-bis(3-carboxy-4-hydroxystyryl)benzene |
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1. D M Skovronsky, et al. Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):7609-14.
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