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Chemical Structure : Sergliflozin etabonate
CAS No.: 408504-26-7
Catalog No.: PC-20194Not For Human Use, Lab Use Only.
Sergliflozin etabonate (GW869682X) is a potent, selective SGLT2 inhibitor with IC50 of 7.5 nM (hSGLT2), >200-fold selectivity over hSGLT1.
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Sergliflozin etabonate (GW869682X) is a potent, selective SGLT2 inhibitor with IC50 of 7.5 nM (hSGLT2), >200-fold selectivity over hSGLT1.
| M.Wt | 448.46 | |
| Formula | C23H28O9 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
ethyl (((2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(2-(4-methoxybenzyl)phenoxy)tetrahydro-2H-pyran-2-yl)methyl) carbonate |
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1. Katsuno K, et al. J Pharmacol Exp Ther. 2007 Jan;320(1):323-30.
2. Pajor AM, et al. J Pharmacol Exp Ther. 2008 Mar;324(3):985-91.
3. Fujimori Y, et al. Eur J Pharmacol. 2009 May 1;609(1-3):148-54.
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