Sotigalimab
(Anti-human CD40 mAb, human IgG1-Kappa; APX005M)
Catalog No.: PC-Ab1065Not For Human Use, Lab Use Only.
Sotigalimab (APX005M) is a humanized monoclonal antibody that binds CD40 with high affinity and activates antigen presenting cells (dendritic cells, monocytes and B cells) leading to stimulation of cancer-specific T-cell responses. This CD40 monoclonal antibody with chemotherapy induces T-cell-dependent tumour regression in mice and improves survival, triggers a multifaceted immune response that brings several components of the immune system together to attack the cancer..
Sotigalimab (APX005M) is a humanized monoclonal antibody that binds CD40 with high affinity and activates antigen presenting cells (dendritic cells, monocytes and B cells) leading to stimulation of cancer-specific T-cell responses. This CD40 monoclonal antibody with chemotherapy induces T-cell-dependent tumour regression in mice and improves survival, triggers a multifaceted immune response that brings several components of the immune system together to attack the cancer.
Physicochemical Properties
M.Wt
Formula
Human IgG1-Kappa
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
PBS, pH 7.0
Contains no stabilizers or preservatives
