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T-1105

Chemical Structure : T-1105

CAS No.: 55321-99-8

T-1105 (T1105)

Catalog No.: PC-62057Not For Human Use, Lab Use Only.

T-1105 is a broad-spectrum antiviral inhibitor that demonstrates good activity for various RNA viruses, including influenza virus, arenaviruses, bunyaviruses, West Nile virus (WNV), yellow fever virus (YFV), FMDV, and ZIKV.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

T-1105 is a broad-spectrum antiviral inhibitor that demonstrates good activity for various RNA viruses, including influenza virus, arenaviruses, bunyaviruses, West Nile virus (WNV), yellow fever virus (YFV), FMDV, and ZIKV; inhibits ZIKV replication with EC50 of 35 uM in a virus yield reduction assay.

Physicochemical Properties

M.Wt 139.114
Formula C5H5N3O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Pyrazinecarboxamide, 3,4-dihydro-3-oxo- (9CI)

References

1. Furuta Y, et al. Antiviral Res. 2009 Jun;82(3):95-102.

2. Zmurko J, et al. PLoS Negl Trop Dis. 2016 May 10;10(5):e0004695.

3. Naesens L, et al. Mol Pharmacol. 2013 Oct;84(4):615-29.

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