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T-3767758

Chemical Structure : T-3767758

CAS No.: 2254733-60-1

T-3767758 (T3767758)

Catalog No.: PC-49283Not For Human Use, Lab Use Only.

T-3767758 is a potent, proline-uncompetitive inhibitor of prolyl-tRNA synthetase (ProRS), displays good activity with EC50 of 595 nM against P. falciparum Dd2-2D4 wild-type parasites.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

T-3767758 is a potent, proline-uncompetitive inhibitor of prolyl-tRNA synthetase (ProRS), displays good activity with EC50 of 595 nM against P. falciparum Dd2-2D4 wild-type parasites.

Physicochemical Properties

M.Wt 364.449
Formula C21H24N4O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(cyclohexanecarboxamido)-N-(2,3-dihydro-1H-inden-2-yl)pyrazine-2-carboxamide

References

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