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Chemical Structure : T-ALZ01
Catalog No.: PC-21288Not For Human Use, Lab Use Only.
T-ALZ01 (CMP-1696) is a small molecule inhibitor of complement component C1r.
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T-ALZ01 (CMP-1696) is a small molecule inhibitor of complement component C1r.
T-ALZ01 (CMP-1696) competitively inhibits C1r through binding of the CCP2-SP region, a functional region conserved in different species such as humans, mice, and rats.
T-ALZ01 (CMP-1696) significantly reduces neuroinflammation in SD microglia cells.
T-ALZ01 (CMP-1696) affects the complement pathway in a dose-dependent manner in SD microglia cell.
T-ALZ01 (CMP-1696) reduces neurodegeneration in the hippocampus and cortex of male and female SD rats.
| M.Wt | 261.28 | |
| Formula | C13H15N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Blake R Rushing, et al. Molecules. 2020 Sep 3;25(17):4016.
2. Terjahna Richards, et al. Res Sq. 2023 Oct 18:rs.3.rs-3399248.
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