T111

Chemical Structure : T111

Catalog No.: PC-25133Not For Human Use, Lab Use Only.

T111 is a potent acridone antimalarial inhibitor against blood, liver, and mosquito stages of malaria parasite, inhibits mitochondrial electron transport chain, has IC50 of 0.028, 0.11 and 0.11 nM for P. falciparum strains Dd2, DR1, and DR4.

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Biological Activity

Physicochemical Properties

M.Wt	423.75
Formula	C20H10ClF4NO3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-chloro-1-fluoro-6-(4-(trifluoromethoxy)phenoxy)acridin-9(10H)-one

References

1. Kelly J, et al. Res Sq [Preprint]. 2025 Jun 27:rs.3.rs-6858328.

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T111

Biological Activity

Physicochemical Properties

References

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