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Chemical Structure : T3D-959
Catalog No.: PC-61599Not For Human Use, Lab Use Only.
T3D 959 (DB-959) is a potent, brain penetrant, orally active dual PPARδ/PPARγ agonist with EC50 of 19/297 nM, respectively.
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T3D 959 (DB-959) is a potent, brain penetrant, orally active dual PPARδ/PPARγ agonist with EC50 of 19/297 nM, respectively; prevents STZ-induced neurotoxicity, and shows clear therapeutic and neuroprotective effects in an established model of sporadic AD.
Alzheimer Disease
Phase 2 Clinical
| M.Wt | 443.47 | |
| Formula | C25H26NNaO5 | |
| Appearance | Solid | |
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| Solubility |
10 mM in DMSO |
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1. Tong M, et al. J Alzheimers Dis. 2016;51(1):123-38.
2. Tong M, et al. J Alzheimers Dis Parkinsonism. 2016 Jun;6(3). pii: 238.
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