Chemical Structure : T7117
CAS No.: 69056-38-8
Catalog No.: PC-26612Not For Human Use, Lab Use Only.
T7117 (6R-BH4 dihydrochloride) is a specific small molecule inhibitor that disrupts the TRIM25-HIF-1α interaction, exerts potent anti‑tumor effects in GBM, also is an orally active phenylalanine hydroxylase (PAH) cofactor, which is effective in reducing blood phenylalanine concentrations.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $98 | In stock | |
| 100 mg | $198 | In stock | |
| 250 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
T7117 (6R-BH4 dihydrochloride) is a specific small molecule inhibitor that disrupts the TRIM25-HIF-1α interaction, exerts potent anti‑tumor effects in GBM, also is an orally active phenylalanine hydroxylase (PAH) cofactor, which is effective in reducing blood phenylalanine concentrations.
| M.Wt | 314.17 | |
| Formula | C9H17Cl2N5O3 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(R)-2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-5,6,7,8-tetrahydropteridin-4(1H)-one dihydrochloride |
|
1. Hui Huang, et al. Cell Death Dis. 2026 Apr 22. doi: 10.1038/s41419-026-08757-3.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright