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Chemical Structure : TAM-16
Catalog No.: PC-60356Not For Human Use, Lab Use Only.
A benzofuran class inhibitor of M. tuberculosis Pks13 (Polyketide Synthase 13).
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A benzofuran class inhibitor of M. tuberculosis Pks13 (Polyketide Synthase 13); show highly potent in vitro bactericidal activity against drug-susceptible and drug-resistant clinical isolates of M. tuberculosis (MICs: 0.06-0.25 uM); exhibits in vivo efficacy in multiple mouse models of TB infection, has excellent pharmacological and safety profiles.
| M.Wt | 380.444 | |
| Formula | C22H24N2O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Aggarwal A, et al. Cell. 2017 Jul 13;170(2):249-259.e25.
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