Catalog No.: PC-27576Not For Human Use, Lab Use Only.
TAS-102 (Trifluridine/tipiracil hydrochloride mixture) is a 1:0.5 mixture of alpha,alpha,alpha-trifluorothymidine (FTD) and 5-chloro-6-[1-(2-iminopyrrolidinyl)methyl]-2,4(1H,3H)-pyrimidinedione hydrochloride thymidine phosphorylase inhibitor (TPI), inhibits thymidilate synthase (TS) and incorporation into DNA.
TAS-102 (Trifluridine/tipiracil hydrochloride mixture) is a 1:0.5 mixture of alpha,alpha,alpha-trifluorothymidine (FTD) and 5-chloro-6-[1-(2-iminopyrrolidinyl)methyl]-2,4(1H,3H)-pyrimidinedione hydrochloride thymidine phosphorylase inhibitor (TPI), inhibits thymidilate synthase (TS) and incorporation into DNA.
Physicochemical Properties
M.Wt
435.76
Formula
C10H11F3N2O5.1/2C9H11ClN4O2.1/2HCl
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
References
1. Emura T, et al. Oncol Rep. 2004 Feb;11(2):381-7.
