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Chemical Structure : TBAJ-587
CAS No.: 2252316-16-6
Catalog No.: PC-49604Not For Human Use, Lab Use Only.
TBAJ-587 is a potent anti-tuberculosis agent, inhibits M.tb strain H37Rv growth with MIC90 of 0.006 and <0.02 µg/mL in MABA and LORA assay, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $228 | In stock | |
| 10 mg | $358 | In stock | |
| 25 mg | Get quote | ||
| 100 mg | Get quote |
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TBAJ-587 is a potent anti-tuberculosis agent, inhibits M.tb strain H37Rv growth with MIC90 of 0.006 and <0.02 µg/mL in MABA and LORA assay, respectively.
TBAJ-587, an analogue of Bedaquiline, demonstrates more potent anti-tubercular activity, with greatly attenuated hERG blockade.
| M.Wt | 614.51 | |
| Formula | C30H33BrFN3O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(1S,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-2-(2,6-dimethoxypyridin-4-yl)-4-(dimethylamino)-1-(2-fluoro-3-methoxyphenyl)butan-2-ol |
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1. Lisa Barbaro, et al. ChemMedChem. 2022 Oct 19;e202200533.
2. Sutherland HS, et al. Bioorg Med Chem. 2019 Apr 1;27(7):1292-1307.
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