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Chemical Structure : TBHQ
Catalog No.: PC-42172Not For Human Use, Lab Use Only.
A phenolic antioxidant and a selective inducer and activator of Nrf2 that ameliorates doxorubicin-induced cardiotoxicity in vivo.
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A phenolic antioxidant and a selective inducer and activator of Nrf2 that ameliorates doxorubicin-induced cardiotoxicity in vivo; ameliorates the doxorubicin-induced oxidative stress and apoptosis, increases the nuclear accumulation of Nrf2 and the Nrf2-regulated gene expression, including HO-1 and NQO-1 expression; also ameliorates early brain injury after experimental subarachnoid emorrhage in mice by enhancing Nrf2-independent autophagy.
| M.Wt | 166.217 | |
| Formula | C10H14O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Lin H, et al. Mol Pharmacol. 2014 May;85(5):682-91.
2. Wang LF, et al. Am J Transl Res. 2015 Oct 15;7(10):1724-35.
3. Li T, et al. Neurochem Res. 2015 Sep;40(9):1829-38.
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