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TCS7010

Chemical Structure : TCS7010

CAS No.: 1158838-45-9

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TCS7010 (Aurora A-IN-10, TCS-7010)

Catalog No.: PC-45948Not For Human Use, Lab Use Only.

TCS7010 is a potent, highly selective Aurora A inhibitor with IC50 of 3.4 nM.

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10 mg $78 In stock
25 mg $128 In stock
50 mg $198 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

TCS7010 is a potent, highly selective Aurora A inhibitor with IC50 of 3.4 nM.
TCS7010 displays >1,000-fold selectivity over Aurora B (IC50=3.4 uM) or CDKs.
TCS7010 is a useful tool compound for investigating the cellular role of Aurora A kinases without the complication of also inhibiting Aurora B.

Physicochemical Properties

M.Wt 588.075
Formula C31H31ClFN7O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Benzamide, N-(2-chlorophenyl)-4-[[2-[[4-[2-(4-ethyl-1-piperazinyl)-2-oxoethyl]phenyl]amino]-5-fluoro-4-pyrimidinyl]amino]-

References

1. Aliagas-Martin I, et al. J Med Chem. 2009 May 28;52(10):3300-7.

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