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Chemical Structure : TDZD-8
CAS No.: 327036-89-5
Catalog No.: PC-42787Not For Human Use, Lab Use Only.
A potent, selective, non-ATP competitive GSK-3β inhibitor with IC50 of 2 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 50 mg | $256 | In stock | |
| 100 mg | $336 | In stock |
Bulk size, bulk discount!
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A potent, selective, non-ATP competitive GSK-3β inhibitor with IC50 of 2 uM; displays no activity against PKA, CK-2, PKC, and CDK1 (IC50>100 uM); reduces the colonic inflammation induced by TNBS in vivo, also prevents 6-OHDA-induced neuronal cell death.
| M.Wt | 222.2636 | |
| Formula | C10H10N2O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
1,2,4-Thiadiazolidine-3,5-dione, 2-methyl-4-(phenylmethyl)- |
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1. Martinez A, et al. J Med Chem. 2002 Mar 14;45(6):1292-9.
2. Whittle BJ, et al. Br J Pharmacol. 2006 Mar;147(5):575-82.
3. Dugo L, et al. Crit Care Med. 2005 Sep;33(9):1903-12.
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