Catalog No.: PC-Ab1030Not For Human Use, Lab Use Only.
TGN1412 is a novel superagonist anti-CD28 monoclonal antibody that directly stimulates T cells. TGN1412 binds to the laterally exposed C′D loop of CD28 and demonstrated its therapeutic potential for use in autoimmune disease, led to a massive and uncontrolled release of proinflammatory cytokines (cytokine storm) during clinical phase I trials..
TGN1412 is a novel superagonist anti-CD28 monoclonal antibody that directly stimulates T cells. TGN1412 binds to the laterally exposed C′D loop of CD28 and demonstrated its therapeutic potential for use in autoimmune disease, led to a massive and uncontrolled release of proinflammatory cytokines (cytokine storm) during clinical phase I trials.
Physicochemical Properties
M.Wt
Formula
Human IgG4P-Kappa
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
PBS, pH 7.0
Contains no stabilizers or preservatives
