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Chemical Structure : TGX286
Catalog No.: PC-20453Not For Human Use, Lab Use Only.
TGX286 is a potent, selective p110β inhibitor with IC50 of 7, 17 and 13 nM for p110β WT, p110β D862Q, and p110β E858H, respectively, >100-fold selectivity over p110α.
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TGX286 is a potent, selective p110β inhibitor with IC50 of 7, 17 and 13 nM for p110β WT, p110β D862Q, and p110β E858H, respectively, >100-fold selectivity over p110α.
| M.Wt | 358.44 | |
| Formula | C23H22N2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Frazzetto M, et al. Biochem J. 2008 Sep 15;414(3):383-90.
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