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Chemical Structure : TH470
CAS No.: 2834739-51-2
Catalog No.: PC-49369Not For Human Use, Lab Use Only.
TH470 (TH-470) is a potent, highly selective type II LIMK1/2 inhibitor with cellular IC50 of 9.8 and 13 nM, respectively.
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TH470 (TH-470) is a potent, highly selective type II LIMK1/2 inhibitor with cellular IC50 of 9.8 and 13 nM, respectively.
TH470 showed excellent selectivity in a comprehensive scanMAX kinase selectivity panel.
| M.Wt | 605.728 | |
| Formula | C30H31N5O5S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-(2-(N-benzyl-4-(N-phenylsulfamoyl)benzamido)ethyl)-2-isobutyramidothiazole-5-carboxamide |
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1. Hanke T, et al. J Med Chem. 2022 Oct 13;65(19):13264-13287.
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