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Chemical Structure : THZ-2-118
Catalog No.: PC-38076Not For Human Use, Lab Use Only.
THZ-2-118 is a potent selective inhibitor of IRAK1 with IC50 of 14.2 nM.
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THZ-2-118 is a potent selective inhibitor of IRAK1 with IC50 of 14.2 nM.
THZ-2-118 does not inhibitor IRAK4 at 10 uM, also potently inhibits JNK1/2/3 (IC50=1-2 nM).
| M.Wt | 493.571 | |
| Formula | C28H27N7O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Hatcher JM, et al. ACS Med Chem Lett. 2020 Oct 9;11(11):2238-2243.
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