TIM-3-IN-1 (TIM-3 inhibitor 38) | TIM-3 inhibitor

Chemical Structure : TIM-3 inhibitor 38

CAS No.: 2883237-04-3

TIM-3 inhibitor 38 (TIM-3-IN-1)

Catalog No.: PC-21024Not For Human Use, Lab Use Only.

TIM-3 inhibitor 38 (TIM-3-IN-1) is a small-molecule inhibitor of T-cell immunoglobulin and mucin domain 3 (TIM-3; HAVCR2) with Ki of 70 nM in FPA competition assays.

Packing	Price	Stock
5 mg	$198	In stock
10 mg	$328	In stock
25 mg	$528	In stock
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Biological Activity

TIM-3 inhibitor 38 (TIM-3-IN-1) is a small-molecule inhibitor of T-cell immunoglobulin and mucin domain 3 (TIM-3; HAVCR2) with Ki of 70 nM in FPA competition assays.

Physicochemical Properties

M.Wt	469.90
Formula	C20H16ClN7O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-(8-Chloro-2-methyl-5-oxo-5,6-dihydro-[1,2,4]triazolo[1,5-c]quinazolin-9-yl)-3-methylphenyl)-1H-imidazole-2-sulfonamide

References

1. Tyson A Rietz, et al. J Med Chem. 2021 Oct 14;64(19):14757-14772.

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TIM-3 inhibitor 38 (TIM-3-IN-1)

Biological Activity

Physicochemical Properties

References

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