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TLR2 agonist C10

Chemical Structure : TLR2 agonist C10

CAS No.: 3095426-02-8

TLR2 agonist C10

Catalog No.: PC-28203Not For Human Use, Lab Use Only.

TLR2 agonist C10 is a potent, selective TLR2 agonist with EC50 of 35 nM, without activating TLR3, TLR4, TLR7 or TLR8.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

TLR2 agonist C10 is a potent, selective TLR2 agonist with EC50 of 35 nM, without activating TLR3, TLR4, TLR7 or TLR8.
C10 induces the secretion of pro-inflammatory cytokines, including IL-1β, IL-6, and TNF-α, in human immune cells.

Physicochemical Properties

M.Wt 423.41
Formula C19H16F3N3O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(5-(2-(methylamino)-5-(methylsulfonyl)phenyl)pyrimidin-2-yl)-5-(trifluoromethyl)phenol

References

1. Zhu Y, et al. ACS Med Chem Lett. 2026 Aug 20;17(9):2017-2026.

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