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Chemical Structure : TP0556351
Catalog No.: PC-38902Not For Human Use, Lab Use Only.
TP0556351 is a highly potent, selective matrix metalloproteinase-2 (MMP2) inhibitor with IC50 of 0.2 nM.
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TP0556351 is a highly potent, selective matrix metalloproteinase-2 (MMP2) inhibitor with IC50 of 0.2 nM.
TP0556351 suppressed the accumulation of collagen in a bleomycin-induced idiopathic pulmonary fibrosis model in mice, demonstrating the efficacy of MMP2-selective inhibitors for fibrosis.
| M.Wt | 1067.164 | |
| Formula | C50H70N10O16 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Tomoki Takeuchi, et al. J Med Chem. 2022 Jun 10. doi: 10.1021/acs.jmedchem.2c00613.
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