TRβ agonist IS25

Chemical Structure : TRβ agonist IS25

Catalog No.: PC-24498Not For Human Use, Lab Use Only.

TRβ agonist IS25 is a potent, selective agonist of thyroid hormone receptor-β (THRβ, TRβ) with EC50 of 458 nM, weakly activates TRα to 30% at 1 uM.

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Biological Activity

TRβ agonist IS25 is a potent, selective agonist of thyroid hormone receptor-β (THRβ, TRβ) with EC50 of 458 nM, weakly activates TRα to 30% at 1 uM.

M.Wt	327.42
Formula	C20H25NO3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(4-(4-amino-3-isopropylbenzyl)-3,5-dimethylphenoxy)acetic acid

1. Perra A, et al. Cell Prolif. 2020 May;53(5):e12808.

2. Runfola M, et al. Eur J Med Chem. 2020 Feb 15;188:112006.