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Chemical Structure : TT-OAD2
Catalog No.: PC-72212Not For Human Use, Lab Use Only.
TT-OAD2 is a potent, selective, non-peptide agonist of glucagon-like peptide-1 (GLP-1) receptor with EC50 of 5 nM.
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TT-OAD2 is a potent, selective, non-peptide agonist of glucagon-like peptide-1 (GLP-1) receptor with EC50 of 5 nM.
TT-OAD2 inhibited GLP-1- and oxyntomodulin-mediated cAMP, calcium, pERK1/2 and β-arrestin responses in a concentration-dependent manner.
TT-OAD2 exhibits biased agonism, and kinetics of G-protein activation and signalling that are distinct from peptide agonists.
| M.Wt | 856.841 | |
| Formula | C50H47Cl2N3O6 | |
| Appearance | Solid | |
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1. Zhao P, et al. Nature. 2020 Jan;577(7790):432-436.
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