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Chemical Structure : TWS119
CAS No.: 601514-19-6
Catalog No.: PC-42674Not For Human Use, Lab Use Only.
A GSK-3β inhibitor with IC50 of 30 nM in a cell-free assay.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 50 mg | $338.4 | In stock | |
| 100 mg | $600 | In stock |
Bulk size, bulk discount!
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A GSK-3β inhibitor with IC50 of 30 nM in a cell-free assay; can induce neurogenesis in murine ESCs; reduces Cdon levels and aberrant Cx43 activitiesin rat cardiomyocytes; attenuates rtPA-induced hemorrhagic transformation and activates the Wnt/β-catenin signaling pathway after acute ischemic stroke in rats.
| M.Wt | 318.3293 | |
| Formula | C18H14N4O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Phenol, 3-[[6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]- |
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1. Ding S, et al. Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7632-7.
2. Wang W, et al. Mol Neurobiol. 2016 Dec;53(10):7028-7036.
3. Jeong MH, et al. Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):E1345-E1354.
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