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Chemical Structure : Tanomastat
Catalog No.: PC-62947Not For Human Use, Lab Use Only.
Tanomastat (BAY 129566) is a potent,orally available, non-peptidic inhibitor of MMP-2, MMP-3 and MMP-9 with 11, 143 and 301 nM, respectively.
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Tanomastat (BAY 129566) is a potent,orally available, non-peptidic inhibitor of MMP-2, MMP-3 and MMP-9 with 11, 143 and 301 nM, respectively.
Tanomastat inhibits extracellular matrix degradation and potentially inhibiting angiogenesis, tumor growth and invasion, and metastasis both in vitro and in vivo.
| M.Wt | 410.912 | |
| Formula | C23H19ClO3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Gatto C, et al. Clin Cancer Res. 1999 Nov;5(11):3603-7.
2. Rowinsky EK, et al. J Clin Oncol. 2000 Jan;18(1):178-86.
3. Leung D, et al. J Med Chem. 2000 Feb 10;43(3):305-41.
4. Moore MJ, et al. J Clin Oncol. 2003 Sep 1;21(17):3296-302.
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