Tarocin B

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Chemical Structure : Tarocin B

Catalog No.: PC-24738Not For Human Use, Lab Use Only.

Tarocin B is a specific inhibitor of UDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase (TarO) with IC50 of 0.41 uM, inhibits the first step in wall teichoic acid biosynthesis, restore β-lactam efficacy against MRSA.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Physicochemical Properties

M.Wt	407.60
Formula	C26H37N3O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(2-cyclohexylbenzimidazol-1-yl)-N-[(1R,2R,4R)-1,7,7-trimethyl-2-bicyclo[2.2.1]heptanyl]propanamide

References

1. Lee SH, et al. Sci Transl Med. 2016 Mar 9;8(329):329ra32.

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Tarocin B

Biological Activity

Physicochemical Properties

References

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