Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : Teclistamab
Catalog No.: PC-38852Not For Human Use, Lab Use Only.
Teclistamab (JNJ-64007957) is a BCMAxCD3 bispecific antibody, recruits and activates T cells to kill BCMA-expressing MM cells.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 1 mg | Get quote | ||
| 5 mg | Get quote | ||
| 10 mg | Get quote | ||
| 25 mg | Get quote | ||
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Teclistamab (JNJ-64007957) is a BCMAxCD3 bispecific antibody, recruits and activates T cells to kill BCMA-expressing MM cells.
Teclistamab induced cytotoxicity of BCMA+ MM cell lines in vitro (H929 cells, EC50=0.15 nM; MM.1R cells, EC50=0.06 nM; RPMI 8226 cells, EC50=0.45 nM).
Teclistamab also depleted BCMA+ cells in bone marrow samples from MM patients in an ex vivo assay with an average EC50 value of 1.7 nM.
Teclistamab demonstrated excellent antitumor activity BCMA+ MM murine xenograft models inoculated with human T cells (tumor inhibition with H929 model and tumor regression with the RPMI 8226 model).
| M.Wt | ||
| Formula | ||
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
