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Chemical Structure : Tedizolid
CAS No.: 856866-72-3
Catalog No.: PC-20075Not For Human Use, Lab Use Only.
Tedizolid (TR-700, DA-7157) is an oxazolidinone antibiotic with activity against mycobacterium tuberculosis and nocardia brasiliensis with MIC50 of 0.25 ug/mL.
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Tedizolid (TR-700, DA-7157) is an oxazolidinone antibiotic with activity against mycobacterium tuberculosis and nocardia brasiliensis with MIC50 of 0.25 ug/mL.
Tedizolid shows MIC50 value 0.25 ug/mL against methicillin-resistant Staphylococcus aureus (MRSA) isolates.
Tedizolid demonstrated greater in vitro potency than linezolid against staphylococci, including linezolid-resistant and vancomycin-nonsusceptible strains, and was 32-fold more active than linezolid against the seven cfr-positive MRSA strains tested.
Tedizolid demonstrated MIC(90) of ≤0.5 μg/ml against clinical isolates of major aerobic and anaerobic bacteria.
| M.Wt | 370.34 | |
| Formula | C17H15FN6O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(R)-3-(4-(2-(2-methyltetrazol-5-yl)-pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyloxazolidin-2-one |
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1. Locke JB, et al. Antimicrob Agents Chemother. 2009 Dec;53(12):5265-74.
2. Vera-Cabrera L, et al. Antimicrob Agents Chemother. 2006 Sep;50(9):3170-2.
3. Yum JH, et al. Antimicrob Agents Chemother. 2010 Dec;54(12):5381-6.
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