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Chemical Structure : Teriflunomide
CAS No.: 163451-81-8
Catalog No.: PC-20268Not For Human Use, Lab Use Only.
Teriflunomide (RS-61980, A-771726) is the active metabolite of leflunomide, acts as an immunomodulatory agent by inhibiting pyrimidine synthesis, inhibits dihydroortate dehydrogenase (DHODH, EC 1.3.3.1) with IC50 of 2.7 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 100 mg | $108 | In stock | |
| 500 mg | $228 | In stock | |
| 1 g | $388 | In stock | |
| 5 g | Get quote |
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Teriflunomide (RS-61980, A-771726) is the active metabolite of leflunomide, acts as an immunomodulatory agent by inhibiting pyrimidine synthesis, inhibits dihydroortate dehydrogenase (DHODH, EC 1.3.3.1) with IC50 of 2.7 uM.
| M.Wt | 270.21 | |
| Formula | C12H9F3N2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)-2-butenamide |
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1. Patterson JW, et al. J Med Chem. 1992 Feb 7;35(3):507-10.
2. Greene S, et al. Biochem Pharmacol. 1995 Sep 7;50(6):861-7.
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