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Chemical Structure : Tetrandrine
Catalog No.: PC-62318Not For Human Use, Lab Use Only.
Tetrandrine (NSC 77037.
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Tetrandrine (NSC 77037;Fanchinine) is a bis-benzylisoquinoline alkaloid that acts a calcium channel blocker (IC50= 8 and 20 uM for L-type and T-type calcium channels, respectively) and induces apoptosis; produces anti-inflammatory, immunomodulating, anti-proliferative, and free radical scavenging effects; has also been shown to increase glucose utilization by enhancing hepatocyte glycogen synthesis; a potent cell autophagy agonist.
Lung Cancer
Phase 3 Clinical
| M.Wt | 622.8 | |
| Formula | C38H42N2O6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Xie QM, et al. Acta Pharmacol Sin. 2002 Dec;23(12):1107-13.
2. Yang Z, et al. Sci Rep. 2016 Jul 26;6:30263.
3. Wang H, et al. Cell Biosci. 2015 Jan 14;5:4.
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