Chemical Structure : Thanatin
CAS No.: 214542-43-5
Catalog No.: PC-28582Not For Human Use, Lab Use Only.
Thanatin is a 21-residue inducible insect defense peptide within antimicrobial activity against fungi and some Gram-positive bacteria with MIC of 0.6-20 uM, disrupts bacterial outer membrane and inactivates the NDM-1 metallo-β-lactamase, inhibits LPS transport (Lpt) LptC-LptA interaction, disrupting the assembly of the Lpt protein machinery.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $128 | In stock | |
| 10 mg | $198 | In stock | |
| 25 mg | $328 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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Thanatin is a 21-residue inducible insect defense peptide within antimicrobial activity against fungi and some Gram-positive bacteria with MIC of 0.6-20 uM, disrupts bacterial outer membrane and inactivates the NDM-1 metallo-β-lactamase, inhibits LPS transport (Lpt) LptC-LptA interaction, disrupting the assembly of the Lpt protein machinery.
| M.Wt | 2433.92 | |
| Formula | C103H177N35O27S3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
Gly-Ser-Lys-Lys-Pro-Val-Pro-Ile-Ile-Tyr-Cys-Asn-Arg-Arg-Thr-Gly-Lys-Cys-Gln-Arg-Met (Disulfide bridge:Cys11-Cys18) |
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1. Fehlbaum P, et al. Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):1221-5.
2. Mandard N, et al. Eur J Biochem. 1998 Sep 1;256(2):404-10.
3. Javadmanesh A, et al. Sci Rep. 2021 May 25;11(1):10890.
4. Ma B, et al. Nat Commun. 2019 Aug 6;10(1):3517.

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