Chemical Structure : Thiazovivin
CAS No.: 1226056-71-8
Catalog No.: PC-43437Not For Human Use, Lab Use Only.
Thiazovivin is a small molecule inhibitor of ROCK, dramatically improves (200-fold) the efficiency of iPSC generation from human fibroblasts.
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Thiazovivin is a small molecule inhibitor of ROCK, dramatically improves (200-fold) the efficiency of iPSC generation from human fibroblasts; dramatically improves the survival of hESCs upon trypsinization, addition of Thiazovivin to cocktail of SB431542 and PD0325901 also vastly improves the survival of iPSCs after splitting by trypsinization; induces porcine embryonic fibroblasts into adipocytes.
M.Wt | ||
Formula | C15H13N5OS | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: ≥ 30 mg/mL |
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Chemical Name/SMILES |
4-Thiazolecarboxamide, N-(phenylmethyl)-2-(4-pyrimidinylamino)- |
1. Lin T, et al. Nat Methods. 2009 Nov;6(11):805-8.
2. Zhu J, et al. Cell Reprogram. 2012 Apr;14(2):99-105.
3. Wang F, et al. Gastroenterology. 2013 Aug;145(2):383-95.e1-21.
4. Mohseni R, et al. Cell Biol Int. 2015 May;39(5):515-8.
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