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Chemical Structure : Ticagrelor
CAS No.: 274693-27-5
Catalog No.: PC-42218Not For Human Use, Lab Use Only.
Ticagrelor (AZD6140) is a potent, selective, reversible and oral P2Y12 receptor antagonist with pKi of 8.7.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 50 mg | $188 | In stock | |
| 100 mg | $298 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
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Ticagrelor (AZD6140) is a potent, selective, reversible and oral P2Y12 receptor antagonist with pKi of 8.7.
Ticagrelor (AZD6140) effectively inhibits platelet aggregation without significant increases in bleeding time in vivo.
Ticagrelor (AZD6140) is used for the prevention of thrombotic events (for example stroke or heart attack) in people with acute coronary syndrome or myocardial infarction with ST elevation.
| M.Wt | 522.5681 | |
| Formula | C23H28F2N6O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
1,2-Cyclopentanediol, 3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-, (1S,2S,3R,5S)- |
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1. VAN Giezen JJ, et al. J Thromb Haemost. 2009 Sep;7(9):1556-65.
2. Husted S, et al. Eur Heart J. 2006 May;27(9):1038-47.
3. Springthorpe B, et al. Bioorg Med Chem Lett. 2007 Nov 1;17(21):6013-8.
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