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Chemical Structure : Tideglusib
CAS No.: 865854-05-3
Catalog No.: PC-49290Not For Human Use, Lab Use Only.
Tideglusib (NP031112, NP-12) is a potent and irreversible small molecule glycogen synthase kinase 3 (GSK-3) inhibitor with IC50 of 60 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $118 | In stock | |
| 50 mg | $188 | In stock | |
| 100 mg | $278 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
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Tideglusib (NP031112, NP-12) is a potent and irreversible small molecule glycogen synthase kinase 3 (GSK-3) inhibitor with IC50 of 60 nM.
Tideglusib (NP031112) is a potent anti-inflammatory and neuroprotective agent against KA-induced in vivo excitotoxicity.
Tideglusib (NP031112) inhibits glutamate-induced glial activation and protects cortical neurons from cell death in vitro.
Tideglusib (NP031112) attenuates glutamate-induced excitotoxic glial activation and neuronal damage.
| M.Wt | 334.393 | |
| Formula | C19H14N2O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
4-benzyl-2-(naphthalen-1-yl)-1,2,4-thiadiazolidine-3,5-dione |
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1. Luna-Medina R, et al. J Neurosci. 2007 May 23;27(21):5766-76.
2. Domínguez JM, et al. J Biol Chem. 2012 Jan 6;287(2):893-904.
3. Serenó L, et al. Neurobiol Dis. 2009 Sep;35(3):359-67.
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