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Tiragolumab

Chemical Structure : Tiragolumab

CAS No.:

Tiragolumab (Anti-human TIGIT mAb, human IgG1-Kappa)

Catalog No.: PC-Ab1006Not For Human Use, Lab Use Only.

The first anti-TIGIT (T-cell immunoglobin and ITIM domain protein) mAb, prevent TIGIT from binding to its ligand, could restore the antitumor response and could complement the activity of anti–PD-L1/PD-1 antibodies. Anti-TIGIT mAb (tiragolumab) has demonstrated promising clinical efficacy in non-small cell lung cancer treatment when combined with an anti-PD-L1 drug (Tecentriq), exhibited remarkable efficacy in PD-L1-positive NSCLC patients in phase II clinical trials..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

The first anti-TIGIT (T-cell immunoglobin and ITIM domain protein) mAb, prevent TIGIT from binding to its ligand, could restore the antitumor response and could complement the activity of anti–PD-L1/PD-1 antibodies. Anti-TIGIT mAb (tiragolumab) has demonstrated promising clinical efficacy in non-small cell lung cancer treatment when combined with an anti-PD-L1 drug (Tecentriq), exhibited remarkable efficacy in PD-L1-positive NSCLC patients in phase II clinical trials.

Physicochemical Properties

M.Wt
Formula Human IgG1-Kappa
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives

Chemical Name/SMILES

References

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