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Chemical Structure : Toceranib phosphate
CAS No.: 874819-74-6
Catalog No.: PC-42529Not For Human Use, Lab Use Only.
An ATP-competitive inhibitor of RTKs, including VEGFR, FGFR, PDGFR, and Kit.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 50 mg | $368 | In stock | |
| 100 mg | $658 | In stock | |
| 500 mg | Get quote |
Bulk size, bulk discount!
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An ATP-competitive inhibitor of RTKs, including VEGFR, FGFR, PDGFR, and Kit; inhibits phosphorylation of WT Kit in the presence of stem cell factor at concentrations as low as 0.01 uM; disrupts function of all forms of mutant Kit in cells.
| M.Wt | 494.4531 | |
| Formula | C22H28FN4O6P | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
1H-Pyrrole-3-carboxamide, 5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-N-[2-(1-pyrrolidinyl)ethyl]-, phosphate (1:1) |
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1. Liao AT, et al. Blood. 2002 Jul 15;100(2):585-93.
2. London CA, et al. Clin Cancer Res. 2003 Jul;9(7):2755-68.
3. London C, et al. Vet Comp Oncol. 2012 Sep;10(3):194-205.
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