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Torezolid phosphate

Chemical Structure : Torezolid phosphate

CAS No.: 856867-55-5

Torezolid phosphate (TR-701, DA-7218)

Catalog No.: PC-20076Not For Human Use, Lab Use Only.

Torezolid phosphate (DR-701, DA-7218) is the pro-drug of Tedizolid (TR-700, DA-7157), could be hydrolysed via phosphatase to form its active metabolite Tedizolid, shows good activity against several Gram positive bacteria, including Nocardia and Mycobacterium.

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Biological Activity

Torezolid phosphate (DR-701, DA-7218) is the pro-drug of Tedizolid (TR-700, DA-7157), could be hydrolysed via phosphatase to form its active metabolite Tedizolid, shows good activity against several Gram positive bacteria, including Nocardia and Mycobacterium.

Physicochemical Properties

M.Wt 450.32
Formula C17H16FN6O6P
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-(3-(3-fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-2-oxooxazolidin-5-yl)methyl dihydrogen phosphate

References

1. Espinoza-González NA, et al. Molecules. 2008 Jan 11;13(1):31-40.

2. Vera-Cabrera L, et al. Antimicrob Agents Chemother. 2006 Sep;50(9):3170-2.

3. Brown SD, et al. Antimicrob Agents Chemother. 2010 May;54(5):2063-9.

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