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Tranylcypromine hydrochloride

Chemical Structure : Tranylcypromine hydrochloride

CAS No.: 1986-47-6

Tranylcypromine hydrochloride (SKF385 hydrochloride)

Catalog No.: PC-24718Not For Human Use, Lab Use Only.

Tranylcypromine (SKF385) hydrochloride is an irreversible inhibitor of lysine-specific demethylase 1 (LSD1, KDM1A) and monoamine oxidase (MAO), inhibits LSD1, MAO-A and MAO-B with IC50s of 20.7, 2.3 and 0.95 μM, respectively.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Tranylcypromine (SKF385) hydrochloride is an irreversible inhibitor of lysine-specific demethylase 1 (LSD1, KDM1A) and monoamine oxidase (MAO), inhibits LSD1, MAO-A and MAO-B with IC50s of 20.7, 2.3 and 0.95 μM, respectively.

Physicochemical Properties

M.Wt 169.65
Formula C9H12ClN
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

trans-2-Phenylcyclopropanamine hydrochloride

References

1. Lee MG, et al. Chem Biol. 2006 Jun;13(6):563-7.

2. Schmidt DM, et al. Biochemistry. 2007 Apr 10;46(14):4408-16.

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