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Triapine

Chemical Structure : Triapine

CAS No.: 143621-35-6

Triapine (3-AP;PAN-811;OCX191;NSC663249)

Catalog No.: PC-42266Not For Human Use, Lab Use Only.

Triapine (3-AP, PAN-811, OCX191, NSC 663249) is a potent ribonucleotide reductase inhibitor with broad spectrum antitumor activity.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Triapine (3-AP, PAN-811, OCX191, NSC 663249) is a potent ribonucleotide reductase inhibitor with broad spectrum antitumor activity.

Ovarian Cancer

Phase 2 Clinical

Physicochemical Properties

M.Wt 195.2449
Formula C7H9N5S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 47 mg/mL

Chemical Name/SMILES

Hydrazinecarbothioamide, 2-[(3-amino-2-pyridinyl)methylene]-

References

1. Liu MC, et al. J Med Chem. 1992 Oct 2;35(20):3672-7.

2. Cory JG, et al. Biochem Pharmacol. 1994 Jul 19;48(2):335-44.

3. Chen RW, et al. Neuroscience. 2005;135(1):191-201.

4. Finch RA, et al. Biochem Pharmacol. 2000 Apr 15;59(8):983-91.

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