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Tubercidin

Chemical Structure : Tubercidin

CAS No.: 69-33-0

Tubercidin (Sparsomycin A, 7-Deazaadenosine, NSC 56408)

Catalog No.: PC-42061Not For Human Use, Lab Use Only.

Tubercidin (7-Deazaadenosine) is an antibiotic and adenosine analog isolated from the bacterium Streptomyces tubercidicus with potential antineoplastic activity.

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Biological Activity

Tubercidin (7-Deazaadenosine) is an antibiotic and adenosine analog isolated from the bacterium Streptomyces tubercidicus with potential antineoplastic activity.
Tubercidin incorporates into DNA and inhibits polymerases, thereby inhibiting DNA replication and RNA and protein synthesis.
Tubercidin also exhibits antifungal and antiviral activities.

Physicochemical Properties

M.Wt 266.2533
Formula C11H14N4O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 30 mg/mL

Chemical Name/SMILES

7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 7-β-D-ribofuranosyl-

References

1. Mooberry SL, et al. Cancer Lett. 1995 Sep 25;96(2):261-6.

2. Olsen DB, et al. Antimicrob Agents Chemother. 2004 Oct;48(10):3944-53.

3. Drew ME, et al. J Biol Chem. 2003 Nov 21;278(47):46596-600.

4. Aoki JI, et al. Parasitol Res. 2009 Jan;104(2):223-8.

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